Agron is known for his sarcastic humor, alongside his brother Duro. Agron had a strong bond with his brother and so he always felt the need to protect him. After Duro's death, Agron seeks revenge with a thirst for Roman blood. Although thirst and fire still burn, he shows a softer and gentler side when he is close to his lover Nasir and maintains a strong friendship with Spartacus as the two evolve to become each other's best friends, embraced like brothers.
While he is friendly and cheerful among those he considers his friends, he is very aggressive and merciless towards those he considers his enemies, regardless of whether they pose a real threat or not. Although Agron has leadership skills, his aggressive nature leads him to make impulsive decisions that put him in many confrontations. Like many of his people, he doesn't like people from different backgrounds.
He distrusts Gauls and Romans in particular, but also most Syrians. However, his trust can be earned, examples being Crixus, Lucius and Nasir, respectively. He also showed his kind side to Laeta while helping her set up a tent, although he once proclaimed that he would kill her if it weren't for Spartacus, his reason for helping her was because he noticed Spartacus's affection for her.